Provectus’s Substack

When an Old Molecule Outsmarts a New Virus

AI, STING, COVID-19, and Provectus’s proprietary synthetic small molecule's Rose Bengal Sodium’s therapeutic intelligence

Nov 12 • 

Provectus Biopharmaceuticals

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October 2025

Investing by the Golden Rule: How One Patient Is Helping Fund Access to Oral PV-10

Sometimes the most powerful principle in life is quite simple: Do unto others as you would have them do unto you

Oct 2 • 

Provectus Biopharmaceuticals

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September 2025

From Surgery to Immunity: How Provectus’s PV-10 and RB-PDAT Can Reimagine the Scalpel in Oncology and Ophthalmology

What if Keytruda could treat two very different diseases, with similar mechanistic intent, like cancer and dermatology, or Humira for dermatology…

Sep 22 • 

Provectus Biopharmaceuticals

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A Provectus/VisiRose Update

Ophthalmology; Injectable solid tumors: Penile squamous cell carcinoma; Veripure; LinkedIn

Sep 2 • 

Provectus Biopharmaceuticals

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August 2025

50+ Years, a Trillion+ Dollars: What America’s “War on Cancer” Has Gotten Us

America entered the war on cancer in 1971. The goal was bold and rather straightforward: find a cure.

Aug 19 • 

Provectus Biopharmaceuticals

Balls in the air; Shots on goal; Looking around corners

In a business context:

Aug 5 • 

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July 2025

Redefining Drug Development: How the FDA’s New Voucher Program Could Accelerate Provectus’s Affordable Cancer Immunotherapy Mission

The Food and Drug Administration (FDA) introduced a new regulatory tool that could reshape the future of drug development.

Jul 24 • 

Provectus Biopharmaceuticals

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When the Treatment Hurts More Than the Disease

In addition to financial toxicity from cancer drugs, it’s time we talk about their life toxicity

Jul 10 • 

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Advancing Across Programs

July 2025 Update

Jul 4 • 

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June 2025

Reassessing Rose Bengal: The 150-Year-Old Textile Dye Reveals Multi-Layered Anti-Cancer Potential as Provectus’s Rose Bengal Sodium Molecule

AI-assisted analysis of ~500 peer-reviewed medical articles from PubMed on “rose bengal” and “cancer”

Jun 26 • 

Provectus Biopharmaceuticals

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Two Golden Rules. One Uncommon Path.

For some, there’s the Golden Rule: “Do unto others as you would have them do unto you.”

Jun 22 • 

Provectus Biopharmaceuticals

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Understanding Rose Bengal Sodium: Biotech Blind Spots and Systems Thinking

For nearly 150 years, rose bengal was seen as a dye. That’s all it’s been allowed to be in the modern pharmaceutical world, until a small biotech began…

Jun 17 • 

Provectus Biopharmaceuticals

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